Preheat oven to 350°F and line a baking sheet with parchment paper.
In a large bowl, mix pumpkin, sugars, butter, egg, and vanilla until smooth.
In a separate bowl, whisk together flour, baking soda, baking powder, salt, and spices.
Slowly stir the dry ingredients into the wet until just combined.
Scoop spoonfuls of dough onto the baking sheet, about 2 inches apart.
Bake for 12–15 minutes or until edges are set and tops look dry.
Cool on the sheet for 5 minutes, then move to a wire rack.